2-methyl-5-nitroimidazole
Alaye ipilẹ:
Orukọ kemikali: 2-methyl-5-nitroimidazole;
Orukọ Gẹẹsi: 2-Methyl-5-nitroimidazole;
CAS nọmba: 88054-22-2
Ilana molikula: C4H5N3O2
Iwọn molikula: 127.1
EINECS nọmba: 618-108-7
Ilana igbekalẹ:
Awọn ẹka ti o jọmọ: awọn ohun elo aise;Awọn agbedemeji elegbogi;Awọn ohun elo aise elegbogi.
iwuwo: 1.4± 0.1g / cm3
Ojutu farabale: 399.5± 15.0 °C ni 760 mmHg
Ojutu yo: 252-254ºC
Filasi ojuami:195.4±20.4 °C
Iwọn gangan: 127.038177
PSA: 74.50000 LogP: -0.10
Irisi: White gara
Ipa oru:0.0±0.9 mmHg ni 25°C
Atọka itọka: 1.592
Awọn ipo ipamọ: edidi ni itura ati agbegbe gbigbẹ ti 0-6ºC
Iduroṣinṣin: kii yoo decompose nigba lilo ati fipamọ ni ibamu si awọn ilana.
| sipesifikesonu | ẹyọkan | boṣewa |
| Ifarahan | Bi funfun tabi yellowish lulú | |
| Akoonu | % | ≥99% |
| Ọrinrin | % | ≤0.3 |
| Sulfate | % | ≤0.3 |
Ni akọkọ lo ninu iṣelọpọ metronidazole, dimetazole ati awọn agbedemeji oogun miiran.
O gba nipasẹ iyọ ti 2-methylimidazole.Fi sulfuric acid, 2-methylimidazole ati sodium sulfate sinu ikoko ifaseyin, ru ati ooru, ṣafikun acid nitric ni 150-160 ℃, ṣafikun, tẹle iṣesi apoti fun wakati kan.Yọ iwọn otutu kuro si 140 ℃ ni isalẹ, lẹhin fifi omi kun pẹlu omi amonia lati ṣatunṣe pH si 3.5-4, crystallization.Igara, wẹ si didoju, gbẹ, 2-methyl-5-nitroimidazole.
25k kraft iwe apo tabi hun apo (58× 110) ila pẹlu ṣiṣu apo, 250kg okeere eiyan apo (100× 80);Gẹgẹbi awọn ibeere alabara;
Ibi ipamọ edidi, ti a fipamọ sinu itura, dudu, ile itaja gbigbẹ, ibi ipamọ ati gbigbe yẹ ki o jẹ ina, lati yago fun ibajẹ ati ọrinrin, ni idinamọ muna pẹlu awọn oogun ti a dapọ.
Ọna iṣelọpọ: Ti gba nipasẹ iyọ ti 2-methylimidazole.Fi sulfuric acid, 2-methylimidazole ati sodium sulfate sinu ikoko ifaseyin, ru ati ooru, ṣafikun acid nitric ni 150-160 ℃, ṣafikun, tẹle iṣesi apoti fun wakati kan.Yọ iwọn otutu kuro si 140 ℃ ni isalẹ, lẹhin fifi omi kun pẹlu omi amonia lati ṣatunṣe pH si 3.5-4, crystallization.Igara, wẹ si didoju, gbẹ, 2-methyl-5-nitroimidazole.
