7-Amino-3-cephem-4-carboxylic acid
Alaye ipilẹ:
English inagijẹ:
7-ANCA;7-AMOCA;(6R,7R) -7-AMIno-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylicAcid;7-NACA;7- NACA,7-ANCA;7-ANCAChemicalbookimpurity;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid
CAS nọmba: 36923-17-8
Ilana molikula: C7H8N2O3S
Iwọn molikula: 200.21
EINECS nọmba: 609-312-7
Ilana igbekalẹ:
Awọn ẹka ti o jọmọ: Awọn agbedemeji Organic; Awọn agbedemeji elegbogi; Awọn ohun elo aise elegbogi.
Yiyọ ojuami: 215-218°C
Ojutu farabale: 536.9± 50.0 °C(Asọtẹlẹ)
Ìwọ̀n: 1.69± 0.1g/cm3(Àsọtẹ́lẹ̀)
Atọka itọka: 1.735 (iṣiro)
Filasi ojuami: 278.508°C
Solubility: Soluble in acidic aqueous ojutu (diẹ, kikan), DMSO (diẹ). Awọn ohun-ini: Funfun tabi funfun lulú kirisita.
Ipa oru: 0mmHg ni 25°C
| sipesifikesonu | ẹyọkan | boṣewa |
| Ifarahan | Funfun tabi funfun lulú kristali | |
| Akọkọ akoonu | % | ≥98.5% |
| Ọrinrin | % | ≤1 |
| Mono arabara | % | ≤0.5 |
| Lapapọ idimu | % | ≤1 |
Cephalosporin, ti a lo bi agbedemeji cefbutan ati cefazoxime.
Sulfuric acid ti o ni idojukọ (104.3mL, 1.92mol) ni a ṣafikun sinu awọn igo mẹta, lẹhinna isophthalic acid (40g, 0.24mol) ti fi kun, ru ati kikan si 60 ℃, ti o waye fun 0.5h, ati 60% nitric acid (37.8g, 0.36) mol) ni a ṣafikun lati ṣakoso alefa isare droplet. Fi sii ni awọn wakati 2. Lẹhin afikun, ifarabalẹ itọju ooru ni 60 ℃ fun awọn wakati 2. Dara si isalẹ 50 ° C, lẹhinna fi 100mL ti omi kun. Awọn ohun elo ti a tutu si otutu otutu, tú sinu àlẹmọ, fifa soke lati yọkuro acid egbin, a ti fọ akara oyinbo ti a fi omi ṣan, ti a fi omi ṣan lati tun ṣe, ati pe ọja funfun jẹ 34.6 giramu, ikore jẹ 68.4%.
20Kg tabi 25Kg/ garawa, garawa paali, ti a fi pẹlu awọ funfun ati apo polyethylene dudu kan. 2℃-8 ℃ gbigbẹ, aye tutu, kuro lati ibi ipamọ ina, wulo fun ọdun 2.
