Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate: Awọn ohun-ini ati Iṣe

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylatejẹ idapọ kẹmika kan pẹlu agbekalẹ molikula C9H6F2O4 ati nọmba CAS 773873-95-3.O tun jẹ mimọ nipasẹ ọpọlọpọ awọn synonyms, gẹgẹbi methyl 2,2-difluoro-1,3-benzodioxole-5-carboxylate, 2,2-difluorobenzodioxole-5-carboxylic acid methyl ester, ati EOS-61003.O jẹ ti kilasi awọn agbo ogun heterocyclic pẹlu atẹgun hetero-atomu nikan.

Iṣogo mimọ ti 98% ti o kere ju, idapọ-oogun elegbogi yii jẹ ojutu ti o wapọ fun awọn ile-iṣẹ bii awọn oogun, awọn agrochemicals, ati research.This yellow is used as key intermediate in the pharmaceutical synthesis, ẹda ti awọn ọja Idaabobo irugbin, ati iwadi ijinle sayensi.

Ninu àpilẹkọ yii, a yoo ṣe apejuwe awọn ohun-ini ọja alaye ati iṣẹ ti methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate, da lori data ti o wa.

Ti ara ati Kemikali Properties

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate jẹ omi alawọ ofeefee ti ko ni awọ tabi ti o lagbara, da lori iwọn otutu ati mimọ.O ni iwuwo molikula ti 216.14 g/mol ati iwuwo ti 1.5± 0.1 g/cm3.O ni aaye gbigbọn ti 227.4± 40.0 °C ni 760 mmHg ati aaye filasi ti 88.9± 22.2 °C.O ni titẹ oru kekere ti 0.1 ± 0.4 mmHg ni 25 ° C ati omi kekere ti 0.31 g / L ni 25 ° C.O ni iye P log ti 3.43, ti o nfihan pe o jẹ diẹ tiotuka ni awọn nkan ti o ni nkan ti ara ju ninu omi.

Ilana ti methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate ni oruka benzene ti a dapọ pẹlu oruka 1,3-dioxole, pẹlu awọn ọta fluorine meji ati ẹgbẹ carboxylate ti a so mọ oruka benzene. .Iwaju awọn ọta fluorine pọ si iduroṣinṣin ati ifaseyin ti agbo, bakanna bi lipophilicity ati bioavailability.Ẹgbẹ carboxylate le ṣe bi ẹgbẹ ti nlọ tabi nucleophile ni ọpọlọpọ awọn aati.Iwọn 1,3-dioxole le ṣe bi glycol ti o boju-boju tabi dienophile ni awọn aati cycloaddition.

Ailewu ati mimu

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate jẹ ipin bi nkan ti o lewu ni ibamu si Eto Irẹpọ Agbaye ti Isọri ati Ifamisi Awọn Kemikali (GHS).O ni awọn alaye ewu wọnyi ati awọn alaye iṣọra:

• H315: Fa irritation ara

• H319: O fa irritation oju pataki

• H335: Le fa irritation ti atẹgun

• P261: Yẹra fun eruku mimi / fume / gaasi / owusuwusu / vapors / sokiri

• P305+P351+P338: Ti o ba wa ni oju: Fi omi ṣan ni iṣọra fun awọn iṣẹju pupọ.Yọ awọn lẹnsi olubasọrọ kuro, ti o ba wa ati rọrun lati ṣe.Tesiwaju fi omi ṣan

• P302+P352: Ti o ba wa ni Awọ: Fọ pẹlu ọpọlọpọ ọṣẹ ati omi

Awọn iwọn iranlọwọ akọkọ fun methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate jẹ bi atẹle:

• Inhalation: Ti o ba jẹ ifasimu, gbe alaisan lọ si afẹfẹ titun.Ti mimi ba ṣoro, fun atẹgun.Ti ko ba simi, fun ni atẹgun atọwọda.Gba itọju ilera

• Awọ ara: Yọ awọn aṣọ ti o ti doti kuro ki o si fi omi ṣan ara daradara pẹlu ọṣẹ ati omi.Ti o korọrun, wa itọju ilera

• Olubasọrọ oju: Awọn ipenpeju lọtọ ati fi omi ṣan pẹlu omi ṣiṣan tabi iyọ deede.Wa itọju ilera lẹsẹkẹsẹ

• Gbigbọn: Gargle, ma ṣe fa eebi.Wa itọju ilera lẹsẹkẹsẹ

Awọn ọna aabo ina fun methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate jẹ atẹle yii:

• Aṣoju apanirun: Pa ina pẹlu owusu omi, erupẹ gbigbẹ, foomu tabi erogba oloro oloro.Yẹra fun lilo omi ṣiṣan taara lati pa ina naa, eyiti o le fa itọjade ti omi flammable ati tan ina naa.

• Awọn eewu pataki: Ko si data wa

• Awọn iṣọra ina ati awọn ọna aabo: Awọn oṣiṣẹ ina yẹ ki o wọ ohun elo mimi afẹfẹ, wọ aṣọ ina ni kikun, ki o ja ina soke.Ti o ba ṣee ṣe, gbe eiyan lati ina lọ si agbegbe ti o ṣii.Awọn apoti ti o wa ni agbegbe ina gbọdọ wa ni kuro lẹsẹkẹsẹ ti wọn ba ni awọ tabi gbe ohun jade lati inu ẹrọ iderun ailewu.Yasọtọ aaye ijamba naa ki o ṣe idiwọ awọn oṣiṣẹ ti ko ṣe pataki lati wọle.Ni ati tọju omi ina lati dena idoti ayika

Ipari

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate jẹ agbedemeji bọtini ni iṣelọpọ elegbogi, ṣiṣẹda awọn ọja aabo irugbin, ati iwadii imọ-jinlẹ.O ni eto alailẹgbẹ pẹlu awọn ọta fluorine meji ati ẹgbẹ carboxylate kan ti a so mọ oruka benzodioxole kan, eyiti o funni ni iduroṣinṣin, ifasẹyin, lipophilicity, ati bioavailability si agbo.O ni solubility omi kekere ati titẹ oru, ati aaye sisun iwọntunwọnsi ati aaye filasi.O ti pin si bi nkan ti o lewu ati nilo mimu to dara ati ibi ipamọ.O ni awọn ohun elo ti o ni agbara ni ọpọlọpọ awọn ile-iṣẹ, bii elegbogi, awọn agrochemicals, iwadii, ati awọn miiran.

Fun alaye siwaju sii tabi awọn ibeere, jọwọpe wa:

Imeeli:nvchem@hotmail.com